News -Imalia Demonstrates Protective Effect of IMA001 in Acute Vaso-occlusion Episode in Sickle Cell Disease Mice

Imalia Demonstrates Protective Effect of IMA001 in Acute Vaso-occlusion Episode in Sickle Cell Disease Mice

Precinical proof-of-concept demonstration of the protective effect of the Administration for 36 days of IMA001 during an acute episode of vaso-occlusion in sickle Townes HbSS mice. IMA001 reduced intravascular hemolysis and inhibited microvascular stasis in animals subjected to an acute hypoxia followed by reoxygenation (8% oxygen for 3 hours and reoxygenation at room air for 1 hour).

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